BULK AND SINGLE-CELL SEQUENCING IDENTIFIED A PROGNOSTIC MODEL BASED ON THE MACROPHAGE AND LIPID METABOLISM RELATED SIGNATURES FOR OSTEOSARCOMA PATIENTS

The introduction of multidrug combination chemotherapy has significantly advanced the long-term survival prospects for osteosarcoma (OS) patients over the past decades.However, the escalating prevalence of chemoresistance has emerged as a substantial impediment to further advancements, necessitating the formulation of innovative strategies.Our pres

Late-term complications of hematopoietic cell transplantation (HCT) are numerous and include incomplete engraftment.One possible mechanism of incomplete engraftment after HCT is cytokine-mediated suppression or dysfunction of the bone marrow microenvironment.Mesenchymal stromal cells (MSCs) elaborate cytokines that nurture or stimulate the marrow m

Background: Many patients consider removal of caries to be a very unpleasant experience.Removal of caries with conventional drill is considered traumatic mainly due to fear and anxiety of children and their parents.Minimally invasive dentistry adopts a philosophy that integrates prevention, remineralization, and minimal intervention for the placeme

Homogeneous mixing in a cavity can be achieved effectively by generating chaotic mixing.However, an improper geometry of cavity with improper fluid motion in it may causes regular motion that is called island.To comprehend the affective chaotic mixing process the study was hbl5266ca carried out in three different geometrics: in between two accentri

Precipitation measurements provide crucial information for hydrometeorological applications.In regions where typical precipitation measurement gauges are sparse, gridded products aim to provide alternative data sources.This study examines the performance of NASA’s Integrated Multi-satellitE Retrievals for the Global Precipitation Measurement